Application Deadline June 30, 2019

We stick to a similar deadline for throwing in your applications for the Werner Risau Prize as last year. So the last chance to apply for this prestigious prize (just have a look at the list of previous winners ) is JUNE 30, 2019! So if you have an interesting story to tell, and which you are prepared to present to an international audience of dedicated cell biologists - hurry up, it`s definitely worth it! And Tübingen is a lovely city anyway with about 1/3 of its population being students…..

The 2018 winner is.....Alban Lonchamp!

We are happy to announce our this year´s winner of the Werner Risau Prize: Dr. Alban Lonchamp, who is currently working as Resident in General Surgery in the Hopital du Valais in Sion, Switzerland. The work related to the project now considered for the Werner Risau Prize was mainly done in the labs of James D. Mitchell and Keith Okazaki at the Harvard University / Brigham and Women´s Hospital in Boston. In the abstract to this study it says"…Here, we report a nutrient-based pathway triggered by dietary restriction of sulfur amino acids, regulating angiogenesis independent of hypoxia or HIF1alpha in mice…" And further: …"Nutrio"-angiogenesis required the amino acid - sensing eIF2alpha kinase GCN2 and the transcription factor ATF4 in ECs. Increased ATF4 promoted expression of VEGF and the hydrogen sulfide (H2S) produced cystathionine-gamma-lyase (CGL). H2S triggered a metabolic switch to glycolysis via inhibition of mitochondrial respiration, thus facilitating rapid ATP production necessary for EC migration…" The discovery of this novel nutrient sensing pathway that appears even targetable by an appropriate diet independent of the hitherto known signaling pathways certainly deserves the acknowledgement given by the Werner Risau Prize. Congratulations!